Test results

Dear A and D

Further to your appointment and subsequently the blood tests done for you both to look for immunological coagulation and genetic factors that may predispose to lack of success for IVF, I now have the details. The chromosome analyses for you both were normal, with no obvious major chromosome anomalies evident that could lead to miscarriage or failure of IVF embryos to implant.

For A we performed a number of studies to look at immune factors that can occur associated with the thyroid gland or lupus antibodies and coagulation antibodies. These were all normal. One of the coagulation studies had a slight change suggesting there could be a genetic change associated with coagulation Factor V Leiden. None of the other coagulation tests or blood tests were abnormal, and in these circumstances and with satisfactory blood clotting findings it is difficult to say if this is contributing at all to your situation. However, it is also considered by some worth trying the use of Heparin from the time of embryo transfer or from early in natural pregnancies. This can be arranged for any further treatment or pregnancy. It would involve injections twice daily until about three months of pregnancy.

The saline ultrasound scan has confirmed a normal appearance of the fallopian tubes and without any adhesions within the uterus. There is a comment that the uterus may have a mild arcuate pattern. This is a very mild difference to the usual pattern the uterus forms in development as a baby. There is no specific treatment or surgery to alter this, and in itself is not sufficient to explain the lack of success with your treatments.

I will enclose with this letter a copy of these investigations and should you wish to discuss any of these further I would be happy to hear from you.

Yours sincerely ...